Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults

Article ID	Journal	Published Year	Pages	File Type
5572080	Clinical Nutrition	2017	9 Pages	PDF

Abstract

Se-supplementation in healthy human adults with marginal Se status resulted in both beneficial and detrimental effects on cellular immunity to flu that was affected by the form of Se, supplemental dose and delivery matrix. These observations call for a thorough evaluation of the risks and benefits associated with Se-supplementation.

Keywords

energy coupled dye SEY ECD MNC APC IFN-γ natural killer allophycocyanin Influenza Cellular immunity Humoral immunity immunoglobulin interleukin tumor necrosis factor alpha SEO SeMet Flu Selenomethionine Selenium Mononuclear cells TNF-α LAK Large granular lymphocytes lymphokine activated killer Lgl Food supplements Interferon gamma

Related Topics

Health Sciences Medicine and Dentistry Critical Care and Intensive Care Medicine

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Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults

Authors

Kamal Ivory, Elena Prieto, Caroline Spinks, Charlotte N. Armah, Andrew J. Goldson, Jack R. Dainty, Claudio Nicoletti,