Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5574582 | Journal of Stroke and Cerebrovascular Diseases | 2016 | 7 Pages |
Abstract
The association of increased basal ganglia perivascular spaces count with reduced von Willebrand factor is novel. As von Willebrand factor may promote cerebral endothelial integrity, insufficient von Willebrand factor is consistent with dysfunctional cerebral endothelium and increased basal ganglia perivascular spaces in cerebral small vessel disease. Quantitative perivascular spaces measurement may increase sensitivity to detect cerebral endothelial dysfunction.
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Authors
Xin PhD, Francesca M. PhD, Maria PhD, Gordon MD, Ann PhD, Kirsten BSc, Fergus MBChB, PhD, Joanna M. FRCR, FRCP, MD, FMedSci,