Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5577943 | The Journal of Pain | 2017 | 9 Pages |
Abstract
The orofacial pain caused by trigeminal nerve damage is severe and perhaps more debilitating than other types of neuropathic pain. However, studies on trigeminal neuropathic pain remain limited. This is largely because of the lack of proper animal models because of the complexity of the existing surgical procedures required to induce trigeminal nerve injury. Our improved dIoN-CCI model is likely to make it more accessible to study the cellular and molecular mechanisms of neuropathic pain caused by trigeminal nerve damage.
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Authors
Weihua Ding, Zerong You, Shiqian Shen, Jinsheng Yang, Grewo Lim, Jason T. Doheny, Lucy Chen, Shengmei Zhu, Jianren Mao,