Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5577952 | The Journal of Pain | 2017 | 36 Pages |
Abstract
Four repeated injections of HS at 48-hour intervals induce a state of persistent hypersensitivity in healthy human participants. This hypersensitivity was characterized by bilateral muscular hyperalgesia and cutaneous cold allodynia, symptoms commonly reported in many chronic pain conditions. Minocycline pretreatment abolished the development of this state.
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Authors
Mohamad Samir Samour, Saad Saulat Nagi, Peter John Shortland, David Anthony Mahns,