Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5578075 | The Journal of Pain | 2017 | 26 Pages |
Abstract
The present study shows an important role of serotonin-1A receptors in morphine-induced hyperalgesia and addiction. It shows that buspirone, a prescription medicine for anxiety and depression can block addictive and hyperalgesic effects of morphine. Clinicians should consider buspirone as adjunctive therapy with morphine to improve therapeutic medications in pain.
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Authors
Darakhshan Jabeen Haleem, Shazia Nawaz,