Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5582175 | International Journal of Obstetric Anesthesia | 2017 | 26 Pages |
Abstract
A thromboprophylactic dose of tinzaparin 4500Â IU had little detectable effect on coagulation as assessed by TEG and anti-Xa assay. These findings support consensus guidelines which state that it is acceptable to perform neuraxial blockade or remove an epidural catheter 10-12Â h after a thromboprophylactic dose of tinzaparin. Rather than suggesting a lack of anticoagulant activity, the findings indicate that TEG may not have the sensitivity to detect a tinzaparin effect when this dose is used in this patient group.
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Authors
S. Griffiths, C. Woo, V. Mansoubi, A. Riccoboni, A. Sabharwal, S. Napier, M. Columb, M. Laffan, G. Stocks,