Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5583075 | Journal of Clinical Anesthesia | 2017 | 14 Pages |
Abstract
In conclusion, these systematic review and meta-analyses of 57 trials confirm that clonidine improves pain control, reduces PONV, improves hemodynamic and sympathetic stability, with no adverse consequences on renal function or awakening time, but does not influence cardiac outcome in the general population, after non-cardiac surgery. Nevertheless, given the high heterogeneity between the studies, this does not exclude different results in patient subgroups or specific procedures.
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Authors
Miguel Carlos Sanchez Munoz, Marc De Kock, Patrice Forget,