| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5583949 | Seminars in Arthritis and Rheumatism | 2017 | 7 Pages |
Abstract
Given spatial heterogeneity of cartilage loss in knee OA, location-independent analysis by MRI may provide opportunity for a paradigm shift. The authors recommend use of a location-independent metrices as the structural endpoints in epidemiological and intervention trials, particularly when examining anabolic and catabolic drug effects. Location-independent methods may be translated to analysis of cartilage composition and other articular tissues.
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Authors
Felix Eckstein, Robert Buck, Wolfgang Wirth,