Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5584655 | Journal of the American Society of Cytopathology | 2017 | 9 Pages |
Abstract
To date, the majority of authors completed their evaluation mostly by including histologic samples of thyroid tumors. Nonetheless, in the last years, a few studies are focusing on the role of miRNA expression in thyroid fine-needle aspiration cytology (FNAC) regardless of the cytologic preparation, including liquid-based cytology. This growing interest is driven by the possible role of miRNAs in the malignant risk stratification, especially for the indeterminate categories of follicular neoplasms (FNs). In this review we overview the reliability of analyzing miRNAs on thyroid lesions, including those diagnosed as FNs, to identify whether their profiles are likely to distinguish benign from malignant lesions, providing a predictive molecular diagnosis on FNAC.
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Authors
Esther Diana MD, PhD, MIAC, Maurizio MD, PhD, Sara BD, PhD, Tonia BD, PhD, Luigi Maria MD,