Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5585217 | Bone | 2017 | 11 Pages |
Abstract
Thus, sparing our patient biopsy of his MEL bone, we identified a heterozygous somatic KRAS mutation in his scleroderma-like dermatosis considered a surrogate for MEL. This implicates postzygotic mosaicism of mutated KRAS, perhaps facilitated by germline LEMD3 haploinsufficiency, causing his MEL.
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Authors
Michael P. Whyte, Malachi Griffith, Lee Trani, Steven Mumm, Gary S. Gottesman, William H. McAlister, Kilannin Krysiak, Robert Lesurf, Zachary L. Skidmore, Katie M. Campbell, Ilana S. Rosman, Susan Bayliss, Vinieth N. Bijanki, Angela Nenninger,