Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5585436 | Bone | 2017 | 35 Pages |
Abstract
HBM is positively associated with OA in non-weight-bearing joints, independent of BMI. HBM-associated OA is characterised by osteophytes, consistent with a bone-forming phenotype, rather than JSN reflecting cartilage loss. Systemic factors (e.g. genetic architecture) which govern HBM may also increase bone-forming OA risk.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
C.L. Gregson, S.A. Hardcastle, A. Murphy, B. Faber, W.D. Fraser, M. Williams, G. Davey Smith, J.H. Tobias,