Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5585827 | Journal of Genetics and Genomics | 2017 | 8 Pages |
Abstract
The adoptive transfer of engineered T cells for the treatment of cancer, autoimmunity, and infectious disease is a rapidly growing field that has shown great promise. Gene editing holds tremendous potential for further improvements of T cell therapy. Here we review the applications of gene editing in various T cell therapies, focusing on antiviral strategies and cancer immunotherapies, and discuss the challenges and future prospects.
Keywords
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Developmental Biology
Authors
Yongping Zhang, Wei Mu, Haoyi Wang,