Article ID Journal Published Year Pages File Type
5586746 Cytokine 2017 8 Pages PDF
Abstract
TRAF6 plays direct roles in the pro-inflammatory effects and proliferation of RA-FLSs. TRAF6 may serve as a potential treatment target in RA.
Keywords
CCL8shRNAECMGFPFITCHRPRANKLICAM-1FLSCXCL2DAPIDMEMLPSACRFACSECLPBSSCIDTBSTTRAF6chemokine (C-X-C motif) ligand 2MMPMCP-2CCK-8cDNAComplementary DNAshort hairpin RNATLRsRheumatoid arthritisOsteoarthritisImmunofluorescenceinterleukinenhanced chemiluminescenceELISAEnzyme-linked immunosorbent assaytumor necrosis factor αfluorescence-activated cell sortingPro-inflammatory cytokinesSynovitiscell counting kit-8tumor necrosis factor receptor-associated factor 6Vascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)TNF-αPhosphate buffered salinefluorescein isothiocyanatelipopolysaccharideExtracellular matrixmatrix metalloproteinasefibroblast-like synoviocytefibroblast-like synoviocytesDulbecco’s modified eagle’s mediumIntercellular adhesion molecule 1polymerase chain reactionPCRHorseradish peroxidasegreen fluorescent proteinPropidium iodideAmerican College of Rheumatologysevere combined immunodeficientToll-like receptors
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Tumor necrosis factor receptor-associated factor (TRAF) 6 inhibition mitigates the pro-inflammatory roles and proliferation of rheumatoid arthritis fibroblast-like synoviocytes
Authors
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