Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5587777 | General and Comparative Endocrinology | 2017 | 5 Pages |
Abstract
The hypothalamus consists of a complex network of distinct neuronal cells, and it is difficult to isolate single-cell populations of GnRH neurons. The establishment of GnRH-expressing cell lines has allowed us to examine the events happening at the single-cell level. In this review, we describe in vitro studies using a GnRH-producing cell model, GT1-7 cells, which have been used to examine how GnRH-producing cells respond to hypothalamic factors and how they are involved in GnRH synthesis.
Keywords
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Endocrinology
Authors
Haruhiko Kanasaki, Aki Oride, Tselmeg Mijiddorj, Unurjargal Sukhbaatar, Satoru Kyo,