Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5587926 | Journal of Clinical and Translational Endocrinology: Case Reports | 2017 | 5 Pages |
Abstract
Glucocorticoid therapies are extensively used in a wide range of medical conditions including respiratory, allergic, inflammatory and autoimmune diseases. Inappropriate use of therapeutic doses of glucocorticoids can lead to many adverse effects including hypothalamic pituitary axis suppression and Cushing's syndrome. All forms of glucocorticoid delivery have the potential to cause Cushing's syndrome. Here we present a case of exogenous Cushing's syndrome resulting from recurrent use of intermittent high dose oral prednisone to treat asthma exacerbation in the emergency department. This case report highlights the importance of pharmacovigilance in emergency departments and ambulatory settings. The knowledge of pharmacokinetic properties, daily dosage, frequency and differences in individual steroid metabolism is crucial in preventing adverse effects related to excessive use of glucocorticoids.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Sanjay MD, MPH, Oguchi MD, FAAFP,