Non-invasive lower limb small arterial measures co-segregate strongly with foot complications in people with diabetes

Likelihood of previous foot complication in this population was ~ 8 times higher when TBI was < 0.6. Such clinical risk profiling was not shown by other non-invasive measures. Prioritizing TBI as a measure of lower-limb vascular disease may be useful to prospectively identify those at risk of diabetic foot complications.