Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5588268 | Journal of Diabetes and its Complications | 2017 | 8 Pages |
Abstract
The field of type 2 diabetes is undergoing a major transformation. Recent cardiovascular outcomes trials of glucose-lowering agents - including EMPA-REG, IRIS and LEADER, have all demonstrated convincing cardiovascular benefits within a relatively short period of time - all likely driven via non-glycemic effects of compounds under study. The implications of these studies (with primary focus on the LEADER trial) - and how their result may be paradigm shifting for type 2 diabetes management, are discussed in this article.
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Authors
Mikhail Kosiborod,