| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5588340 | Metabolism | 2017 | 10 Pages |
Abstract
We conclude a regulating role of TSH on hepatic PCSK9 expression, which further contributing to a higher LDL-c level.
Keywords
FXRProprotein convertase subtilisin kexin 9CYP8B1HNF-4αPCSK9LRH-1TSHRSREBPfT3FT4LDLRCYP7A1MFIHMGCRHDL-CLDL-CTSH3-hydroxy-3-methylglutaryl-CoA reductasefarnesoid X receptorSCHtriglycerideFree thyroxineFree triiodothyroninehepatocyte nuclear factor 4αhigh-density lipoprotein cholesterolliver receptor homologue-1thyroid stimulating hormoneSterol regulatory element-binding proteinProprotein convertase subtilisin/kexin type 9total cholesterolLow-density lipoprotein cholesterolSubclinical hypothyroidismLow-density lipoprotein receptorThyroid stimulating hormone receptor
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Authors
Yingyun Gong, Yizhe Ma, Zhengqin Ye, Zhenzhen Fu, Panpan Yang, Beibei Gao, Wen Guo, Dandan Hu, Jingya Ye, Shuai Ma, Fan Zhang, Li Zhou, Xinyu Xu, Zhong Li, Tao Yang, Hongwen Zhou,