Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5588379 | Metabolism | 2017 | 9 Pages |
Abstract
Incident type 2 diabetes is associated with HDL cholesterol but not with its anti-oxidant constituent - PON-1 - in a large cohort of apparently healthy men and women. The current data question the importance of PON-1 activity for the development of diabetes.
Keywords
HOMA-IRPrevention of Renal and Vascular End-stage DiseasePREVENDPON-1CKD-EPIHDL-CEGFRSBPAntioxidanthomeostasis model assessment of insulin resistanceUAEstandard deviationcardiovascular diseaseUrinary albumin excretionType 2 diabetesCVDbody mass indexBMIRisk factorsconfidence intervalsystolic blood pressurehigh-density lipoprotein cholesterolestimated glomerular filtration ratehazard ratioChronic Kidney Disease Epidemiology CollaborationParaoxonaseParaoxonase-1HDL cholesterol
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Authors
Setor K. Kunutsor, Lyanne M. Kieneker, Stephan J.L. Bakker, Richard W. James, Robin P.F. Dullaart,