Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5588401 | Metabolism | 2017 | 20 Pages |
Abstract
During hydrocortisone infusion, BAT temperature increased both under fasting basal conditions and during β-AR stimulation. We observed a BAT temperature threshold, which was not exceeded despite maximal β-AR activation. We conclude that BAT thermogenesis is present in humans under near-normal conditions. Glucocorticoids modulate BAT function, representing important physiological endocrine regulation of body temperature at times of acute stress.
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Authors
Hannah Scotney, Michael E. Symonds, James Law, Helen Budge, Don Sharkey, Konstantinos N. Manolopoulos,