| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5588403 | Metabolism | 2017 | 11 Pages |
Abstract
Thus, the present study highlights the deleterious role that the amygdalar PTP1B has on energy homeostasis in obesity states. The reduction of PTP1B in the CeA may be a strategy for the treatment of obesity, insulin resistance and anxiety disorders.
Keywords
SF-1LMO4IL-10BATPOMCNPYHFDPTP1BEPMNSFRERASOmRNApro-opiomelanocortinPEPCKPI3KCeANFκBantisense oligonucleotideUcp1AmygdalaAktAnxietyinsulinInterleukin 10brown adipose tissueelevated plus mazetumor necrosis factor-alphaCNSmessenger ribonucleic acidhigh-fat dietendoplasmatic reticulumcentral nervous systemSteroidogenic factor 1TNF-αnuclear factor kappa Bphosphoenolpyruvate carboxykinasephosphoinositide 3-kinaseObesityfood intakeRespiratory exchange ratiocentral nucleus of the amygdalaProtein tyrosine phosphatase 1Buncoupling protein 1protein kinase Binsulin receptorNeuropeptide Y
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Authors
Natalia Ferreira Mendes, Gisele Castro, Dioze Guadagnini, Natalia Tobar, Susana Quiros Cognuck, Lucila Leico Kagohara Elias, Patricia Aline Boer, Patricia Oliveira Prada,