| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5588425 | Metabolism | 2017 | 17 Pages |
Abstract
Our findings reveal the sequential adipogenic events directed by PARL-PINK1-Parkin system, add more evidence supporting the convergence of pathogenesis leading to neurodegenerative and metabolic diseases, and provide substantial information for developing novel therapeutic strategies by manipulating adipogenesis.
Keywords
Mdivi-1mitofusin-1Peroxisome proliferator-activated receptor-γ (PPARγ)PTEN-induced kinase 1MCEPARLT2DMMfn1PI3KDrp1PINK1GSK-3βFABP4PPARγIL-4Adipogenesisinterleukin-4Type 2 diabetes mellitusParkindynamin-related protein-1PtenPeroxisome proliferator-activated receptor gammaMitotic clonal expansionGlycogen synthase kinase-3β
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Authors
Ming-Yuh Shiau, Pin-Shen Lee, Ying-Jyun Huang, Ching-Ping Yang, Chiao-Wan Hsiao, Kai-Yun Chang, Huan-Wen Chen, Yih-Hsin Chang,