| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5588438 | Metabolism | 2017 | 25 Pages |
Abstract
Our findings suggest that increased serum zonulin concentration, i.e., increased intestinal permeability, contributes to metabolic endotoxemia, systemic inflammation, and insulin resistance in overweight pregnant women. By reinforcing intestinal barrier, it may be possible to manipulate maternal metabolism during pregnancy with subsequent health benefits.
Keywords
Low grade inflammationHOMA2-IRLPSIL-6QUICKIhs-CRPPCAOverweightmetabolic endotoxemiainterleukin-6Pregnancycardiovascular diseasePrincipal component analysistumor necrosis factor-αCVDbody mass indexBMIquantitative insulin sensitivity check indexTNF-αlipopolysaccharideIntestinal permeabilityHigh-sensitive C-reactive proteinGlycA
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Kati Mokkala, Outi Pellonperä, Henna Röytiö, Pirkko Pussinen, Tapani Rönnemaa, Kirsi Laitinen,