| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5588517 | Metabolism | 2017 | 7 Pages |
Abstract
Women with GDM have significantly higher fetuin B levels as compared to healthy pregnant control women and GDM status, insulin resistance, and fetuin A positively predict circulating fetuin B. Postpartum fetuin B is decreased as compared to prepartum values suggesting a placental co-secretion of this novel adipokine/hepatokine. Further studies need to elucidate factors contributing to fetuin B regulation in humans, as well as the pathophysiological significance of fetuin B upregulation in GDM.
Keywords
hsCRPT2DOGTTHbA1cHOMA-IRGDMFFAHDLAFABPHepatokineAdipokineOral glucose tolerance test (OGTT)homeostasis model assessment of insulin resistanceFree fatty acidsAmerican Diabetes AssociationFasting insulinTriglyceridesELISAEnzyme-linked immunosorbent assayHigh sensitivity C Reactive ProteinGestational diabetes mellitusType 2 diabetes mellitusbody mass indexBMIIn vitro fertilizationIVFhigh density lipoproteinlow density lipoproteinLDLInsulin resistanceGlycated hemoglobin A1cADAAdipocyte fatty acid-binding proteinFasting glucose
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Authors
Susan Kralisch, Annett Hoffmann, Ulrike Lössner, Jürgen Kratzsch, Matthias Blüher, Michael Stumvoll, Mathias Fasshauer, Thomas Ebert,