Article ID Journal Published Year Pages File Type
5589498 Gene 2016 12 Pages PDF
Abstract
New mutations were generated at different locations within the promoter region of ATG16L2 gene and added to a plasmid construct containing a luciferase gene reporter gene. The results show a clear relationship between the distance of the novel AUGs from initiation codon and protein expression. The inhibitory effect was even stronger when multiple AUG sequences were present in 5′ UTR.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
Authors
, ,