Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5589498 | Gene | 2016 | 12 Pages |
Abstract
New mutations were generated at different locations within the promoter region of ATG16L2 gene and added to a plasmid construct containing a luciferase gene reporter gene. The results show a clear relationship between the distance of the novel AUGs from initiation codon and protein expression. The inhibitory effect was even stronger when multiple AUG sequences were present in 5â² UTR.
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Authors
Ruslan Al-Ali, Rogelio González-Sarmiento,