| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5589525 | Gene | 2017 | 7 Pages |
Abstract
GCC haplotype carriers showed higher probability to have RH (odds ratio > 1), while the GCT haplotype carriers showed lower probability to have RH, suggesting that the GCT haplotype may represent a protective genetic factor for the development of RH. These finds suggest that GCC and GCT haplotypes, and C allele and CC genotype of the â 735C/T MMP-2 gene polymorphism may have a role in RH.
Keywords
MMP-2tissue inhibitor of metalloproteinases 2TODTIMP-2PWVLVMILVHHbA1cABPMASEDBPSBPSNPsMmpsTarget organ damageAmerican Society of EchocardiographyLeft ventricularCardiovascular diseasesanalysis of varianceANOVAEnzyme-linked immunosorbent assayELISACVDPulse wave velocitybody mass indexBMILeft ventricular mass indexdiastolic blood pressuresystolic blood pressureBlood pressurecardiovascularLow-density lipoproteinLDLmatrix metalloproteinase 2Matrix metalloproteinasesambulatory blood pressure monitoringGlycated hemoglobinLeft ventricular hypertrophypolymerase chain reactionPCRrefractory hypertensionresistant hypertensionSingle nucleotide polymorphismsGenetic polymorphism
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Genetics
Authors
Andrea R. Sabbatini, Natalia R. Barbaro, Ana Paula de Faria, Alessandra Mileni V. Ritter, Rodrigo Modolo, Nathália B. Correa, Veridiana Brunelli, Claudio Pinho, Vanessa Fontana, Heitor Moreno,