Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling

Article ID	Journal	Published Year	Pages	File Type
5589609	Gene	2017	9 Pages	PDF

Keywords

NGS VSD LQTS QTc KV7.1 PDB RMSD SCD KCNE1 Kv2.1 KCNQ1 BWA GOF Burrows-Wheeler aligner DNA VUS amino acid Cardiopulmonary resuscitation CPR deoxyribonucleic acid ECG electrocardiogram Gain of function Next generation sequencing SUD Voltage sensor domain CAM Long QT syndrome corrected QT interval root mean square distance transmembrane Molecular Operating Environment Protein modeling Sudden cardiac death Sudden unexplained death milliseconds Mink wildtype MOE Protein Data Bank Molecular autopsy Calmodulin

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Genetics

Preview

Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling

Authors

Erika Antúnez-Argüelles, Arturo Rojo-DomÃnguez, Ana Leticia Arregui-Mena, Leonor Jacobo-Albavera, Manlio Fabio Márquez, Pedro Iturralde-Torres, MarÃa Teresa Villarreal-Molina,