| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5589749 | Gene | 2017 | 6 Pages |
Abstract
C677T MTHFR gene polymorphism is associated with RA in Egyptians. MTHFR 677TT carriers had higher concentrations of serum Hcy than did subjects harboring the CC and CT genotypes. The presence of 677T allele increases the risk of atherosclerosis in patients with RA. This increased risk of atherosclerosis could be due to hyperhomocysteinemia.
Keywords
MTHFRCIMTORSDASCISESRRheumatoid arthritiscardiovascular diseaseanalysis of varianceANOVATriglyceridesELISAtHcyCVDPCR–RFLPerythrocyte sedimentation ratebody mass indexBMICarotid intima-media thicknessrheumatoid factorconfidence intervalsmethylene tetrahydrofolate reductaseodds ratiosDisease activity scoreC-reactive proteinCRPGene polymorphismpolymerase chain reaction–restriction fragment length polymorphismtotal cholesterol
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Authors
Tarek A. Abd El-Aziz, Rasha H. Mohamed,