| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5589947 | Gene | 2016 | 7 Pages |
Abstract
Our study evidenced that obesity risk genes generated multi-variant effects, which can be additive or non-linear interactions, and multi-variant study is an important supplement to existing GWAS for understanding genetic effects of obesity risk genes.
Keywords
MDRNRXN3JHSCHRNA3GIPRTFAP2BMC4RGRsNegr1HWEMAFSNPsBDNFHardy-Weinberg equilibriumGene-gene interactionfat mass and obesity associatedstandard errorPrediction errorFTObody mass indexBMILinkage disequilibriumBrain-derived neurotrophic factorminor allele frequencyObesityJackson Heart StudyGenome-wide association studyGWASprincipal componentgenetic risk scoreHaplotypeSingle nucleotide polymorphismsMultifactor dimensionality reductionmelanocortin 4 receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Genetics
Authors
Shijian Liu, James G. Wilson, Fan Jiang, Michael Griswold, Adolfo Correa, Hao Mei,