| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5590749 | Multiple Sclerosis and Related Disorders | 2017 | 23 Pages |
Abstract
NFI-MS scale is equally sensitive as FSS scale for assessment of MS fatigue; thus, it may also be widely used to evaluate that symptom. Generally HPA axis is hyperactive in MS patients, but it is not correlated with fatigue in our study. For the first time, levels of CLIP (a type of melanocortin) are studied, and determined to be lower among MS patients. Elevated levels of IL-35 and IL-2 suggest that these cytokines may have a prominent role in MS pathophysiology and can be investigated as potential targets for development of novel therapies.
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Authors
Aylin Akcali, Fatma Zengin, Sefika Nur Aksoy, Orhan Zengin,