| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5591889 | Molecular Immunology | 2017 | 7 Pages |
Abstract
Our results suggest that anti-M3R autoantibodies in primary Sjögren's syndrome induce downregulation of plasma membrane-resident M3R and MHC class I molecules in leukocytes followed by NK cell-mediated cell death. This mechanism may explain the frequency of leukopenia occurrence in patients with primary Sjögren's syndrome.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Molecular Biology
Authors
Eun Namkoong, Sang-woo Lee, Nahyun Kim, Youngnim Choi, Kyungpyo Park,