Hypoxia-induced ADAM 17 expression is mediated by RSK1-dependent C/EBPÎ² activation in human lung fibroblasts

Article ID	Journal	Published Year	Pages	File Type
5591928	Molecular Immunology	2017	9 Pages	PDF

Keywords

CTGF sIL-6rα RSK1 TNF RSK TNF-α-converting enzyme TACE HIF ECL COA ECM IPF HRP SSC NF-κB PBS IgG FBS MMP c/ebpβ CCAAT/enhancer-binding protein β Small interfering RNA siRNA Rheumatoid arthritis systemic sclerosis nonessential amino acids SDS-PAGE sodium dodecylsulfate polyacrylamide gel electrophoresis chromatin immunoprecipitation immunoglobulin G enhanced chemiluminescence A disintegrin and metalloproteinase 17 minimum essential medium fetal bovine serum Hypoxia-inducible factor Connective tissue growth factor tumor necrosis factor nuclear factor-κB Lung fibrosis idiopathic pulmonary fibrosis Extracellular matrix matrix metalloproteinase MEM Phosphate-buffered saline Hypoxia polymerase chain reaction PCR Horseradish peroxidase CHiP

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology

Hypoxia-induced ADAM 17 expression is mediated by RSK1-dependent C/EBPÎ² activation in human lung fibroblasts

Authors

Jing-Yun Chen, Chien-Huang Lin, Bing-Chang Chen,