| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5593662 | Physiology & Behavior | 2017 | 7 Pages |
Abstract
TL1 and TL3 were not significantly modified by the different treatments. MK-801 increased TL2 compared to control group leading a disruption of spatial memory processing which was markedly attenuated by Clz. WAY-100635 suppressed this action supporting a relevant role of 5-HT1A-R in the Clz mechanism of action to improve spatial memory dysfunction. Although a significant decrease of hippocampal BDNF levels underlies the learning/memory impairment induced by MK-801, this effect was not significantly prevented by Clz.
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Authors
Ximena López Hill, AnalÃa Richeri, MarÃa Cecilia Scorza,