| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5597050 | The Annals of Thoracic Surgery | 2016 | 6 Pages |
Abstract
MMP-2/JNK apoptotic and β1D-integrin/FAK survival pathways are activated in the nonischemic adjacent zone after MI in adult sheep. LVAD unloading of approximately 50% cardiac output for 2 weeks attenuates remodeling in part by its negative effect on stretch-induced apoptosis and inhibition of MMP-2 activity.
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Authors
Tieluo MD, Xufeng MD, PhD, Charles F. MD, Pablo G. MD, PhD, Shuying MD, Zhongjun J. PhD, Bartley P. MD,