A Meta-Analysis of Miniaturized Versus Conventional Extracorporeal Circulation in Valve Surgery

The effects of miniaturized extracorporeal circulation in patients operated on for heart valve surgery are still inconsistent. We performed a meta-analysis of eight studies involving 1,011 patients to evaluate the comprehensive effects of miniaturized extracorporeal circulation. The results suggested its application significantly reduced the length of stay in the intensive care unit and total hospital stay after heart valve surgery, but no significant effects on reducing postoperative morbidity and mortality were observed. Further studies with long-term follow-up are needed to confirm our results.