Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5597353 | The Annals of Thoracic Surgery | 2017 | 8 Pages |
Abstract
Alcohol supplementation substantially reduced postoperative pericardial adhesion formation, attenuated pericardial thickening, and reduced myocardial fibrosis in response to chronic ischemia. Alcohol supplementation modulates adhesion protein and MMP/tissue inhibitor of metalloproteinase expression, favoring a profile associated with reduced pericardial adhesions. These results suggest that the myocardium is the driving factor in reducing pericardial adhesions and mediating the postoperative healing process.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Nassrene Y. MD, Ashraf A. MD, Antonio D. MD, Rahul S. MD, Frank W. MD,