Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5597993 | Annals of Vascular Surgery | 2017 | 7 Pages |
Abstract
Clostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. This case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to C. septicum bacteremia. Subsequent evaluation confirmed a colonic malignancy, prompting early intervention. A systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, and hematologic malignancy is 3.9%, with the remaining cohort of patients having an unknown source. Infectious involvement of the aorta and associated vascular structures portends a poor prognosis with a 57% mortality rate. Our case and updated review demonstrates the implications of C. septicum vascular seeding and subsequent treatment outcomes.
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Authors
Yewande Alimi, Michael Sosin, Tracy M. Borsinger, John R. Garrett, J.R. Salameh, C. Francisco Espinel,