Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599618 | Atherosclerosis | 2017 | 9 Pages |
Abstract
Proposed cholesterol thresholds for childhood FH screening were less accurate than previously estimated. A sequential strategy of biochemical screening followed by targeted sequencing of FH genes in screen-positive children may help mitigate the higher than previously estimated FPR and reduce wasted screening of unaffected parents.
Keywords
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Authors
Marta Futema, Jackie A. Cooper, Marietta Charakida, Christopher Boustred, Naveed Sattar, John Deanfield, Debbie A. Lawlor, Nicholas J. Timpson, UK10K Consortium UK10K Consortium, Steve E. Humphries, Aroon D. Hingorani,