Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599649 | Atherosclerosis | 2017 | 30 Pages |
Abstract
Uremia modulates the phenotype of aortic SMCs as determined by mRNA/miRNA expression, an increased medial area, and decreased aortic contractility. We propose that this phenotypic modulation of SMCs precedes the acceleration of atherosclerosis observed in uremic mice.
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Authors
Marie Madsen, Annemarie Aarup, Sebastian Albinsson, Karsten Hartvigsen, Charlotte M. Sørensen, Karolina Turczynska, Lars B. Nielsen, Tanja Xenia Pedersen,