Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599723 | Atherosclerosis | 2016 | 5 Pages |
Abstract
Microvesicles are formed under many circumstances, especially in atheromatous plaques. Erythrocyte-derived microvesicles (ErMVs) have been proved to promote atherosclerosis by promoting hypercoagulation, mediating inflammation and inducing cell adhesion. Several clinical studies have reported potential roles of ErMVs in cardiovascular disease diagnosis, but the current understanding of ErMVs remains insufficient. In this paper, we will review current research on the formation and degradation of ErMVs and the possible effects of ErMVs in atherosclerosis, discuss potential clinical applications in cardiovascular disease, and hope to raise awareness of the relation with atherosclerosis.
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Authors
Kai-Yin Li, Lei Zheng, Qian Wang, Yan-Wei Hu,