Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599726 | Atherosclerosis | 2016 | 7 Pages |
Abstract
Lysosomal oxLDL accumulation within macrophages contributes to murine atherosclerosis. Future intervention strategies should focus specifically on preventing oxLDL, unlike non-modified LDL, from being internalized into lysosomes. Such an intervention can have an additive effect to current existing treatments against atherosclerosis.
Keywords
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Authors
Mike L.J. Jeurissen, Sofie M.A. Walenbergh, Tom Houben, Marion J.J. Gijbels, Jieyi Li, Tim Hendrikx, Yvonne Oligschlaeger, Patrick J. van Gorp, Christoph J. Binder, Marjo M.P.C. Donners, Ronit Shiri-Sverdlov,