Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599739 | Atherosclerosis | 2016 | 27 Pages |
Abstract
The spectrum of mutations in the Asian Indian population is quite heterogeneous. Of the mutations identified, 40% were novel. No mutation was observed in exons 3, 9 and 14 of LDLR gene, which are considered to be hot spots in studies done on Asian Indians in South Africa. Early detection followed by aggressive therapy, and cascade screening of extended families has been initiated to reduce the morbidity and mortality in these patients.
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Authors
Nitika Setia, Renu Saxena, Anjali Arora, Ishwar C. Verma,