| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5601200 | Chest | 2006 | 10 Pages |
Abstract
Four dominant qualities of dyspnea in asthma (inspiratory difficulty, chest tightness, unsatisfied inspiration, and work) were reported early in the course of MCT and evolved in parallel, becoming more prevalent at maximum response. Significant DH accompanied even mild bronchoconstriction during MCT in asthma, making it difficult to separate mechanisms of chest tightness from other dominant respiratory sensations.
Keywords
TLCFRCMCTPEFFEF75ICSKingston General HospitalKGHFEF50forced expiratory flow at 50% of FVCPC20EFLmethacholine challenge testingAsthmaLong-acting β-agonistSymptom perceptionDyspneaDynamic hyperinflationPeak expiratory flowLABAinspiratory capacityFunctional residual capacityTotal lung capacityprovocative concentration of methacholine causing a 20% fall in FEV1MethacholineExpiratory flow limitation
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Authors
Lougheed MD, FCCP, Fisher RRT, O'Donnell MD, FCCP,