Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5601204 | Chest | 2006 | 7 Pages |
Abstract
Epithelial mucin stores are increased in habitual smokers because of goblet cell hypertrophy and hyperplasia, and the pattern of mucin gene expression is abnormal. The highest epithelial mucin stores are found in smokers with airflow obstruction, suggesting a mechanistic link between epithelial mucin dysregulation and airflow obstruction.
Keywords
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Authors
Innes MD, Woodruff MD, Ferrando MA, Donnelly PhD, Dolganov PhD, Lazarus MD, Fahy MD,