Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5601920 | European Journal of Vascular and Endovascular Surgery | 2017 | 12 Pages |
Abstract
Transcriptomic and lncRNA-mRNA correlation analysis revealed HOTAIR was downregulated in STAA and associated with genes involved in extracellular matrix remodelling. In vitro experiments confirmed that knockdown of HOTAIR could induce apoptosis and suppress collagen types I and III expression in human aortic smooth muscle cells.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
X. Guo, Q. Chang, H. Pei, X. Sun, X. Qian, C. Tian, H. Lin,