Sick sinus syndrome with HCN4 mutations shows early onset and frequent association with atrial fibrillation and left ventricular noncompaction

Article ID	Journal	Published Year	Pages	File Type
5603437	Heart Rhythm	2017	22 Pages	PDF

Abstract

SSS with HCN4 mutations may form a distinct SSS subgroup characterized by early clinical manifestation after adolescence and frequent association with AF and LVNC.

Keywords

SCN5A HCN4 mutation Sick sinus syndrome Left ventricular noncompaction Atrial fibrillation Pacemaker

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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Sick sinus syndrome with HCN4 mutations shows early onset and frequent association with atrial fibrillation and left ventricular noncompaction

Authors

Taisuke DVM, PhD, Seiko MD, PhD, Takashi MD, PhD, Kentaro MD, PhD, Hiroyuki DDS, PhD, Tetsuya MD, Hiroki MPharm, Risa Sakamoto, Takafumi Ohkusa, Takeshi MD, PhD, Akihiko MD, PhD, Naokata MD, PhD, Wataru MD, PhD, Koh-ichiro MD, PhD, Hitoshi MD, PhD,