| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5604672 | International Journal of Cardiology | 2017 | 6 Pages |
Abstract
Cardio-respiratory control imbalance is a common finding in early type 1 diabetes. A reduced sensitivity to hypoxia seems a primary factor leading to reflex sympathetic activation (enhanced hypercapnic chemoreflex and baroreflex depression), hence suggesting a functional origin of cardio-respiratory control imbalance in initial diabetes.
Keywords
FEV1HVRCXCR4FVCeNOSBRSSDF-1GSHDLCOHIF-1T1DSDNNChemoreflexEPCHCVRGLO-1TV, Tidal volumeHRVROSminute ventilationBaroreflex sensitivityAutonomic nervous systemType 1 diabetesbaroreflexEndothelial progenitor cellsendothelial nitric oxide synthasediffusing capacity of the lung for carbon monoxideforced vital capacityhypoxia-inducible factor-1Vascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)end-tidal carbon dioxide pressureMethylglyoxalMgOdiabetic neuropathyheart rate variabilityC-X-C chemokine receptor type 4HypoxiaGlutathioneGlyoxalase-1Reactive oxygen species
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Authors
L. Bianchi, C. Porta, A. Rinaldi, C. Gazzaruso, P. Fratino, P. DeCata, P. Protti, R. Paltro, L. Bernardi,