Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5605009 | International Journal of Cardiology | 2017 | 15 Pages |
Abstract
In the present study acute infusion of levosimendan in isolated rabbit hearts resulted in an abbreviation of atrial action potential duration and a reduction of aERP. This led to a significantly elevated inducibility of atrial fibrillation. These results suggest a proarrhythmic effect of levosimendan regarding atrial fibrillation. This aspect should be further investigated in the clinical setting.
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Authors
Gerrit Frommeyer, Anja Kohnke, Christian Ellermann, Dirk G. Dechering, Simon Kochhäuser, Florian Reinke, Michael Fehr, Lars Eckardt,