Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5605205 | International Journal of Cardiology | 2017 | 27 Pages |
Abstract
Compared to their younger counterparts, elderly have a higher incidence of disease-related morbidities, take more medicines and account for more adverse drug related events. Similarly, women present several differences in CVD pathophysiology, clinical manifestations and outcomes in comparison to their male counterparts. For these reasons, the results of RCTs obtained in younger men cannot be simply translated in elderly and women. Unfortunately, although international guidelines have been published to increase the enrolment of elderly and women, their recruitment is still insufficient. Thus, the inclusion of these subgroups in cardiovascular RCTs is a key aspect to acquire evidence-based knowledge in the understanding and management of CVDs in elderly and women.
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Authors
Cristiana Vitale, Massimo Fini, Ilaria Spoletini, Mitja Lainscak, Petar Seferovic, Giuseppe MC Rosano,