Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5605442 | International Journal of Cardiology | 2017 | 24 Pages |
Abstract
In this study, myostatin and pSmad2 were significantly up-regulated in the failing heart of female patients, but not male patients, and female patients displayed lower body mass index. Enhanced myostatin signaling in female failing heart may causally contribute to pathogenesis of HF and cardiac cachexia.
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Authors
Junichi Ishida, Masaaki Konishi, Masakazu Saitoh, Markus Anker, Stefan D. Anker, Jochen Springer,